Veterinarian formulated for use in dogs over the age of 12 weeks. Our unique blend of Thiamine and L-Tryptophan help reduce stress and tension, Melatonin helps to promote rest and relaxation, and Ginger helps to settle sensitive stomachs, which is especially important during travel. Helps to promote a calming effect during situational stressful events such as storms, fireworks, travel, and grooming.